ITM Leaf - Institute For Translational Medicine (2024)

Your Gateway to Clinical Research Explorations

Get access to millions of patient datapoints in just seconds.

Take the guesswork out of evaluating cohort feasibility.

Search data across diseases, populations, and health systems.

OVER 2.2 MILLION PATIENTS


Five Years in the Making

Now you have a really helpful research tool at your fingertips thanks to the Institute for Translational Medicine (ITM) and its collaborators across Chicago and the National Institutes of Health National Center for Advancing Translational Sciences (NCATS).

Leaf is the first discovery tool of its kind in Chicagoland. With just a few clicks, you can explore data across patient populations and filter according to things like age, medical conditions, and even procedures. ITM Leaf was made possible thanks to support from NCATS’ Clinical and Translational Science Awards Program grant number UL1TR002389. Please cite the grant in your work to ensure tools like this can continue to help researchers like you!

Testimonials

ITM Leaf - Institute For Translational Medicine (2)

Eric Bhaimia, D.O.

Assistant Professor

Rush University Medical Center

The Leaf cohort discovery tool provides a gateway for clinicians and researchers to perform impactful research. In Leaf, researchers can take an idea or observation and query the databases. This ensures that research efforts are focused on addressing the healthcare needs of today, and how they may impact tomorrow.

ITM Leaf - Institute For Translational Medicine (3)

Graeme Forrest, MBBS

Professor of Medicine


Department of Internal Medicine 


Division of Infectious Diseases


RUSH Medical College

As a clinical researcher running clinical trials and implementation science, having rapid access to data both locally and regionally into the number of patients that could be enrolled or impacted by a study is critically important with many submissions. Now having access to the LEAF database has already helped considerably in determining opportunities for future studies. I am able to enter the diagnoses I am interested in, the types of populations that are affected, in this case oncology and it gives me numbers of patients seen with that condition in the last 3 years, locally and at other sites nearby. As a pre-screening tool, it helps justify numbers on research submissions and when applying for prospective studies for my site. Before this was available, it was a guess, or I had to wait for data from the repository, now I can do it in minutes from my computer. If you are a researcher, leaf will simplify the process to justify powering a study and make querying data before research and IRB submission a lot faster.

ITM Leaf - Institute For Translational Medicine (4)

How can this information help you?

See if there are enough patients who would qualify for your study, or use the information to prepare an IRB protocol or grant proposal!


The Leaf cohort discovery tool provides a gateway for clinicians and researchers to perform impactful research. In Leaf, researchers can take an idea or observation and query the database. This ensures that research efforts are focused on addressing the healthcare needs of today, and how they may impact tomorrow.

Who can access Leaf?

Researchers at the University of Chicago, RUSH, and Loyola University Chicago who are eligible to be on an IRB-approved study can access LEAF using your institutional credentials. You don’t need an approved IRB protocol to access Leaf. 
Leaf is behind a security firewall, so you’ll need to connect via your institution’s VPN or be on campus to access it.

Get Started with ITM Leaf

Access your ITM institution’s Leaf platform

Click your institution's logo below to get started! Remember to login using your VPN or campus connection.

ITM Leaf - Institute For Translational Medicine (5)

ITM Leaf - Institute For Translational Medicine (6)

ITM Leaf - Institute For Translational Medicine (7)

Want to Learn More? Watch These Videos on How to Use the Tool

Intro

Basic query

Federated query

Tips

Excited to dive in or have any questions? Connect with Suzi Birz at Suzi.Birz@uchicagomedicine.org.

Learn more about Leaf and how it was created in this paper from the Journal of the American Medical Informatics Association.

ITM Leaf - Institute For Translational Medicine (8)

ITM Leaf - Institute For Translational Medicine (9)

About the Institute for Translational Medicine (ITM)

The Institute for Translational Medicine (ITM) helps you live your best life by making research breakthroughs happen and getting those discoveries into the real world to improve your health as soon as possible.

We’re part of a network of more than 50 CTSA Program-supported hubs across the country working to slash the time it takes to develop and share new treatments and health approaches. We work with you and for you to make participating in health research easy, so that together we improve health care for all.

Join the movement and learn more about how we help researchers, physicians, community members, industry, government organizations, and others. Visit us at chicagoitm.org and connect with us on Facebook, Twitter, Instagram, YouTube, and LinkedIn @ChicagoITM.

Be social with us @ChicagoITM

Want to be an ITM Insider? Tell us what you want to know and we'll send it direct to your Inbox.

Find Out More

Copyright © 2024 Institute for Translational Medicine (ITM). All Rights Reserved.
ITM Leaf - Institute For Translational Medicine (2024)

FAQs

What is the difference between translational and clinical medicine? ›

Clinical research is medical research that involves people like you. ... Translational research is research that applies discoveries generated in the laboratory to studies in humans (bench to bedside), or that speeds the adoption of best practices into community settings (bedside to practice).

What is considered translational medicine? ›

Often described as an effort to carry scientific knowledge “from bench to bedside,” translational medicine builds on basic research advances—studies of biological processes using cell cultures, for example, or animal models—and uses them to develop new therapies or medical procedures.

What is translational biomedicine? ›

Translational medicine is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach.

What is translational medicine and therapeutics? ›

Translational Medicine aims to improve human health and longevity by moving new preclinical discoveries e.g. of new drugs or other interventions to their evaluation in man ('bench-to-bedside').

What is the ranking of clinical and translational medicine? ›

Clinical and Translational Medicine (CTM)'s 2022 Impact Factor is 10.6, according to the 2022 Journal Citation Report. Among 136 SCI-indexed 'Medicine, Research & Experimental' journals in the world, CTM ranks 14th (top 10.3%, Q1 category).

How much does it cost to publish in the Journal of Translational Medicine? ›

APC payment

APCs will allow continued Open Access to all of The Journal of Translational Medicine articles. Authors are asked to pay US$525 if their article is accepted for publication. Waiver requests will be considered on a case-by-case basis, by the Editor-in-Chief.

What is an example of translational medicine? ›

One prime example of translational research in human disease is the study of cancer therapy. Extensive cooperation between basic researchers, clinicians, and industry has generated numerous new targeted compounds with enhanced efficacy and decreased toxicity.

What is the most likely purpose or application of translational medicine? ›

Translational medicine seeks to coordinate the use of new knowledge in clinical practice and to incorporate clinical observations and questions into scientific hypotheses in the laboratory.

What is translational medicine from bench to bedside? ›

Medical science typically follows this rule, beginning at the bench of a basic science laboratory with an observation at a molecular or cellular level, and gradually progressing through different levels and obstacles until used in the clinical setting of the bedside, or vice versa.

What is bench to bedside? ›

(bench ... BED-side) A term used to describe the process by which the results of research done in the laboratory are directly used to develop new ways to treat patients.

What is reverse translational medicine? ›

Reverse Translational Medicine™ (RTM™) is Neurimmune's proprietary technology platform. It is based on the scientific understanding and high-throughput analyses of human immune responses to disease-related proteins in selected populations including elderly with the capability to stay healthy during the aging process.

What is translational medicine course? ›

Overview. The PG program in Translational Medicine is designed to equip students with the knowledge and skills to bridge the gap between basic scientific research and the development of medical applications/products through translational research pathways.

What is the short name for science translational medicine? ›

The abbreviation of the journal title "Science translational medicine" is "Sci. Transl. Med.". It is the recommended abbreviation to be used for abstracting, indexing and referencing purposes and meets all criteria of the ISO 4 standard for abbreviating names of scientific journals.

What is the translational medicine field? ›

Translational medicine lies at the interface between basic research, with the quest to understand the mechanisms of disease development, and clinical research which aims to assess the efficiency and safety of new treatments for patients.

What is MRes translational medicine? ›

The MRes in Biomedical Sciences and Translational Medicine programme will enable you to develop an advanced knowledge of biomedical sciences and its application to translational medicine. It will allow you the opportunity to specialise in distinct basic and applied research pathways.

What does clinical medicine mean? ›

Clinical medicine is the branch of medicine that deals with the diagnosis and treatment of diseases in human beings. It is also concerned with the prevention of disease and the promotion of health. Clinical medicine includes both primary care and specialty care.

What is an example of translational research in medicine? ›

Showcase: Translational Research in Action
  • Breast Cancer Detection / Piezoelectric Fingers / Biosensors Platform. Science Behind iBreastExam Innovation. ...
  • Chronic Wound Healing / Biomedical Ultrasonics: Sensors Platform. New Hope for Healing Chronic Wounds. ...
  • Traumatic Brain Injury / Near Infrared Based Optical Imaging Platform.

What is clinical and translational neuroscience? ›

Clinical and Translational Neuroscience (CTN) is a peer-reviewed scientific journal that publishes original research articles, literature- systematic and critical reviews, short communications and case reports in the areas of transdisciplinary neuroscience research.

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